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PERF: SequentialSeqFileRandomAccess FASTA indexer does per-line regex on sequence lines

Status: Open.

#5197 In biopython/biopython;

· mmokrejs opened on Apr 17, 2026

Clarification on chain.id mapping in MMCIFParser: asym_id vs auth_asym_id

Status: Open.

#5195 In biopython/biopython;

· MaybeBio opened on Apr 15, 2026

Making Location objects hashable?

Enhancement

Status: Open.

Feature

#5193 In biopython/biopython;

· manulera opened on Apr 14, 2026

Bio.Phylo.write Newick default precision (%1.5f) causes silent data loss for small branch lengths

Status: Open.

#5184 In biopython/biopython;

· Wytamma opened on Mar 31, 2026

GenBank parsing - handle misplaced BASE COUNT line

Status: Open.

#5172 In biopython/biopython;

· manulera opened on Mar 3, 2026

C++ acceleration for mmCIF parsing (native "fast path" for coordinates)

Status: Open.

#5156 In biopython/biopython;

· Felixburton7 opened on Jan 27, 2026

Missing libm linkage causes undefined symbol errors

Status: Open.

#5137 In biopython/biopython;

· BwL1289 opened on Jan 9, 2026

MMCif2Dict doesn't parse all keys in extremely large structures

Status: Open.

#5136 In biopython/biopython;

· jonahZoldan-mfi opened on Jan 8, 2026

PDBParser is not thread-safe when used in ThreadPoolExecutor

Status: Open.

#5131 In biopython/biopython;

· yiyabo opened on Jan 5, 2026

Why does read_PIC_seq give different distances and angles for each residue?

Status: Open.

#5119 In biopython/biopython;

· HakonOnco opened on Dec 8, 2025

Proposal: Optional ProteinSeq class for protein sequences

Status: Open.

#5115 In biopython/biopython;

· harisj739 opened on Nov 30, 2025

IC_residue's get_angle function gives different results for psi and "N:CA:C:1N"

Status: Open.

#5113 In biopython/biopython;

· HakonOnco opened on Nov 28, 2025