diff --git a/packages/compiler/src/render3/view/i18n/meta.ts b/packages/compiler/src/render3/view/i18n/meta.ts
index f5071b3f8fc5..081c96da53c9 100644
--- a/packages/compiler/src/render3/view/i18n/meta.ts
+++ b/packages/compiler/src/render3/view/i18n/meta.ts
@@ -12,7 +12,10 @@ import * as i18n from '../../../i18n/i18n_ast';
 import {createI18nMessageFactory, VisitNodeFn} from '../../../i18n/i18n_parser';
 import * as html from '../../../ml_parser/ast';
 import {ParseTreeResult} from '../../../ml_parser/parser';
+import {splitNsName} from '../../../ml_parser/tags';
 import * as o from '../../../output/output_ast';
+import {SecurityContext} from '../../../core';
+import {DomElementSchemaRegistry} from '../../../schema/dom_element_schema_registry';
 import {isTrustedTypesSink} from '../../../schema/trusted_types_sinks';
 
 import {hasI18nAttrs, I18N_ATTR, I18N_ATTR_PREFIX, icuFromI18nMessage} from './util';
@@ -49,6 +52,18 @@ const setI18nRefs = (originalNodeMap: Map<html.Node, html.Node>): VisitNodeFn =>
   };
 };
 
+const domSchema = new DomElementSchemaRegistry();
+
+function isIframePolicyTranslatedAttribute(tagName: string, attrName: string): boolean {
+  const elementName = splitNsName(tagName)[1];
+
+  return (
+    elementName.toLowerCase() === 'iframe' &&
+    domSchema.securityContext(elementName, attrName, /* isAttribute */ true) ===
+      SecurityContext.ATTRIBUTE_NO_BINDING
+  );
+}
+
 /**
  * This visitor walks over HTML parse tree and converts information stored in
  * i18n-related attributes ("i18n" and "i18n-*") into i18n meta object that is
@@ -201,14 +216,20 @@ export class I18nMetaVisitor implements html.Visitor {
         } else if (attr.name.startsWith(I18N_ATTR_PREFIX)) {
           // 'i18n-*' attributes
           const name = attr.name.slice(I18N_ATTR_PREFIX.length);
-          let isTrustedType: boolean;
+          let isSecuritySensitive: boolean;
           if (node instanceof html.Component) {
-            isTrustedType = node.tagName === null ? false : isTrustedTypesSink(node.tagName, name);
+            isSecuritySensitive =
+              node.tagName === null
+                ? false
+                : isTrustedTypesSink(node.tagName, name) ||
+                  isIframePolicyTranslatedAttribute(node.tagName, name);
           } else {
-            isTrustedType = isTrustedTypesSink(node.name, name);
+            isSecuritySensitive =
+              isTrustedTypesSink(node.name, name) ||
+              isIframePolicyTranslatedAttribute(node.name, name);
           }
 
-          if (isTrustedType) {
+          if (isSecuritySensitive) {
             this._reportError(
               attr,
               `Translating attribute '${name}' is disallowed for security reasons.`,
diff --git a/packages/core/test/acceptance/security_spec.ts b/packages/core/test/acceptance/security_spec.ts
index 884fea63c168..39a52b79bdc9 100644
--- a/packages/core/test/acceptance/security_spec.ts
+++ b/packages/core/test/acceptance/security_spec.ts
@@ -752,7 +752,7 @@ describe('iframe processing', () => {
           },
         );
 
-        it('should work when a security-sensitive attributes are marked for translation', () => {
+        it('should error when iframe policy attributes are marked for translation', () => {
           @Component({
             selector: 'my-comp',
             template: ` <iframe src="${TEST_IFRAME_URL}" i18n-sandbox sandbox=""> </iframe> `,
@@ -761,7 +761,9 @@ describe('iframe processing', () => {
           })
           class IframeComp {}
 
-          expectIframeToBeCreated(IframeComp, {src: TEST_IFRAME_URL});
+          expect(() => TestBed.createComponent(IframeComp)).toThrowError(
+            /Translating attribute 'sandbox' is disallowed for security reasons./,
+          );
         });
       });
     });